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What is ankylosing spondylitis?

Published in Autoimmune Disease 2 mins read

What is Ankylosing Spondylitis?

Ankylosing spondylitis (AS) is a specific type of arthritis characterized by chronic inflammation primarily affecting the spine and large joints, leading to stiffness and pain.

Understanding the Name

The term "ankylosing spondylitis" itself offers insights into the nature of the condition:

Part of Word Meaning Relevance to Ankylosing Spondylitis
Ankylosing Stiff or rigid Refers to the progressive stiffness and potential fusion it causes.
Spondyl Spine Indicates its primary impact on the spinal column.
Itis Inflammation Highlights the inflammatory process at the root of the disease.

What Ankylosing Spondylitis Affects

While its primary focus is the spine, causing inflammation in the vertebrae, ankylosing spondylitis can also involve other parts of the body. This inflammation can lead to discomfort and limited mobility, particularly in the lower back, buttocks, and neck. Over time, if left unmanaged, the inflammation can lead to the formation of new bone, potentially causing sections of the spine to fuse, further restricting movement and posture.

Beyond the spinal column, AS can also cause inflammation in:

  • Large joints: Commonly including the hips, shoulders, and heels.
  • Entheses: The points where tendons and ligaments attach to bone.
  • Other organs: Less commonly, it can affect the eyes, heart, or lungs.

Key Characteristics and Symptoms

The common signs and symptoms of ankylosing spondylitis often include:

  • Persistent Back Pain: This pain is typically worse in the mornings or after periods of inactivity and tends to improve with exercise or movement.
  • Stiffness: A noticeable stiffness in the back, particularly in the morning, which can restrict flexibility.
  • Fatigue: A pervasive feeling of tiredness, often due to the body's chronic inflammatory response.

Early diagnosis and consistent management are vital for individuals with AS. This helps to control symptoms, slow disease progression, prevent significant spinal damage, and maintain a good quality of life. For more comprehensive information, you can consult reputable medical resources such as Johns Hopkins Medicine or the Spondylitis Association of America.