Many drugs, particularly a class of medications known as dihydropyridine calcium channel blockers, commonly end in the suffix "-pine."
The "-pine" suffix serves as a common identifier for a significant group of pharmaceutical agents within the dihydropyridine calcium antagonist class. These medications are widely utilized for their therapeutic effects on the cardiovascular system, primarily by influencing blood vessel relaxation and heart function.
Dihydropyridine Calcium Channel Blockers Ending in "-pine"
Drugs in this category function as calcium channel blockers. They work by impeding the movement of calcium into the cells of the heart and blood vessel walls. This action causes blood vessels to relax and widen, which can lower blood pressure, reduce the heart's workload, and help treat conditions like high blood pressure (hypertension) and angina (chest pain).
Here is a list of common dihydropyridine calcium channel blockers that end with the "-pine" suffix:
| Drug Name | Common Brand Name(s) | Class (Suffix Relevance) | Primary Use Example (General) |
|---|---|---|---|
| Amlodipine | Norvasc | Dihydropyridine Calcium Antagonist | Hypertension, Angina |
| Felodipine | Plendil | Dihydropyridine Calcium Antagonist | Hypertension, Angina |
| Isradipine | Dihydropyridine Calcium Antagonist | Hypertension | |
| Nicardipine | Cardene | Dihydropyridine Calcium Antagonist | Hypertension, Angina |
| Nifedipine | Adalat CC | Dihydropyridine Calcium Antagonist | Hypertension, Angina |
| Nimodipine | Nymalize | Dihydropyridine Calcium Antagonist | Prevents vasospasm after hemorrhage |
| Nitrendipine | Dihydropyridine Calcium Antagonist | Hypertension |
These medications are essential tools in managing various cardiovascular disorders due to their specific mechanism of action in relaxing vascular smooth muscle.
