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What is the generic name for Avastin?

Published in Cancer Drug Generic Name 2 mins read

The generic name for Avastin is bevacizumab.

Understanding Generic and Brand Names in Medicine

In the pharmaceutical industry, medications typically have two primary names: a brand name (or trade name) and a generic name. Understanding the difference is crucial for patients and healthcare providers.

  • Brand Name: This is the proprietary name given by the pharmaceutical company that developed and markets the drug. It's often a memorable, registered trademark, such as Avastin. Companies invest significantly in marketing brand names.
  • Generic Name: This is the official, non-proprietary name of the drug's active ingredient. It's universally recognized and often more complex, like bevacizumab. Generic drugs contain the same active ingredient, strength, dosage form, and route of administration as their brand-name counterparts.

Bevacizumab (Avastin): A Targeted Cancer Treatment

Bevacizumab is a type of targeted cancer drug treatment. It is recognized for its role in inhibiting the growth of new blood vessels that tumors need to grow and spread, a process known as angiogenesis.

Category Name Description
Generic Name Bevacizumab The active pharmaceutical ingredient.
Brand Name Avastin The commercial name for the drug, marketed by Genentech/Roche.
Drug Class Targeted Therapy Specifically, a monoclonal antibody (anti-VEGF agent).

How Targeted Therapies Work in Cancer Treatment

Targeted therapies, including bevacizumab, represent a significant advancement in cancer treatment. Unlike traditional chemotherapy that affects all rapidly dividing cells, targeted drugs are designed to interfere with specific molecules involved in cancer cell growth, progression, and spread.

Bevacizumab specifically targets a protein called vascular endothelial growth factor (VEGF). VEGF is a critical signaling protein that stimulates the formation of new blood vessels. By blocking VEGF, bevacizumab can:

  • Inhibit the growth of new blood vessels that supply oxygen and nutrients to tumors.
  • Shrink existing blood vessels that feed the tumor.
  • Slow the growth and spread of the cancer.

This targeted approach often results in fewer side effects compared to conventional chemotherapy because it primarily affects cancer cells and their supporting structures, rather than healthy cells.

For comprehensive information on cancer treatments, including targeted therapies like bevacizumab, reputable organizations such as the National Cancer Institute or the Mayo Clinic offer extensive resources.