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What Medications Can Worsen Neuropathy?

Published in Drug-Induced Neuropathy 1 min read

Many medications, particularly those used for chemotherapy, certain immune conditions, and viral infections, are known to worsen or induce neuropathy.

Medications Known to Worsen Neuropathy

Peripheral neuropathy, a condition characterized by damage to nerves outside the brain and spinal cord, can be an adverse effect of various pharmaceutical agents. Understanding which medications can contribute to or exacerbate neuropathy is crucial for patient care and management. The following table outlines categories of drugs and specific examples known to have this effect:

Medication Category Specific Medications
Chemotherapeutic Agents Cisplatin, Oxaliplatin, Taxanes, Vinca Alkaloids, Bortezomib, Suramin, Misonidazole
TNF-alpha Inhibitors Infliximab, Etanercept
Antiretroviral Agents Zalcitabine, Didanosine, Stavudine
Cardiac Medications Amiodarone, Perhexiline, Statins
Thalidomide Thalidomide

It is important for individuals experiencing neuropathy symptoms while on these medications to consult with their healthcare provider. Management often involves careful monitoring, dose adjustments, or considering alternative treatments, depending on the severity of symptoms and the necessity of the medication.