The "dark side" of Entresto primarily refers to its potential side effects and risks, which, like any medication, can range from mild and common to severe and requiring immediate medical attention. Understanding these potential downsides is crucial for patients and healthcare providers.
Understanding Entresto's Potential Side Effects
While Entresto is an effective medication for heart failure, its therapeutic benefits must be weighed against its safety profile. Patients taking Entresto may experience various adverse reactions.
Common Side Effects
Many individuals may experience common side effects that are generally manageable and often diminish over time as the body adjusts to the medication. These include:
- Dizziness and Fainting: Especially when standing up quickly.
- Light-headedness: A sensation of nearly fainting.
- Cough: A persistent cough.
- Headache: Mild to moderate headaches.
- Diarrhoea: Loose or frequent stools.
- Feeling Sick (Nausea): An unsettled stomach.
- Stomach Pain: Discomfort in the abdominal area.
- Tiredness and Weakness: General fatigue or lack of energy.
Serious Side Effects (Angioedema Risk)
Of greater concern are the serious side effects, which require immediate medical attention. The most significant and potentially life-threatening serious side effect associated with Entresto is angioedema. This condition involves rapid swelling beneath the skin, particularly affecting the face and airways.
Signs of serious side effects include:
- Swelling of the face, lips, tongue, and/or throat: This can be sudden and severe.
- Difficulty breathing and/or swallowing: This is a medical emergency as it indicates potential airway obstruction.
If you experience any of these serious side effects, it is imperative to seek emergency medical help immediately. Angioedema can quickly become life-threatening if not addressed promptly.
For comprehensive information regarding Entresto and its safety profile, it is advisable to consult official medication guides from reputable health authorities, such as the Medsafe Consumer Medicine Information (CMI) for Entresto.