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Who has the closest DNA to you?

Published in Genetic Relationships 2 mins read

Your full sibling has the closest DNA to you, sharing on average 50% of your DNA.

When considering who has the closest genetic material to you, the answer lies in your immediate family members due to the direct inheritance of DNA from your parents. The amount of shared DNA decreases as the familial relationship becomes more distant.

Understanding DNA Inheritance

You inherit 50% of your DNA from your mother and 50% from your father. Your siblings also inherit 50% from each parent, but the specific segments of DNA they receive from each parent will be a different, random combination than yours. This genetic shuffling, known as recombination, is why siblings are not identical (unless they are identical twins), but still share a significant portion of their DNA.

Average DNA Shared Between Relatives

The average percentage of DNA shared provides a clear picture of genetic closeness. This measure helps in understanding familial ties and can be particularly useful in genealogy and genetic testing.

Here's a breakdown of the average DNA shared with various relatives:

Relationship Average % DNA Shared
Full Sibling 50%
Grandparent / Grandchild 25%
Aunt / Uncle 25%
Niece / Nephew 25%
Half Sibling 25%
1st Cousin 12.5%
Great-grandparent / Great-grandchild 12.5%
Great-Uncle / Aunt 12.5%
Great Nephew / Niece 12.5%
1st Cousin once removed 6.25%
Half first cousin 6.25%

As the table illustrates, the highest average percentage of shared DNA is with a full sibling, confirming their position as your closest genetic relative outside of a parent-child relationship.

Why Different Percentages?

The percentages reflect the degree of common ancestry and the way genetic material is passed down through generations. For instance:

  • Full Siblings: Share the same two parents, leading to a high degree of shared genetic material.
  • Half Siblings, Grandparents/Grandchildren, Aunts/Uncles, Nieces/Nephews: Share one common ancestor (a parent or grandparent), resulting in approximately half the DNA shared with full siblings.
  • First Cousins: Share a set of grandparents, meaning their common genetic material is further diluted through more generations.

For more information on how DNA is inherited, you can explore resources on genetics and heredity from reputable organizations like the National Human Genome Research Institute: Learn About Genetics.