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Which color topped evacuated tube is most commonly associated with hematology testing?

Published in Hematology Tubes 3 mins read

Which color topped evacuated tube is most commonly associated with hematology testing?

The lavender or pink-topped evacuated tube is most commonly associated with hematology testing.


The Indispensable Role of Lavender/Pink Tubes in Hematology

For a wide array of blood tests crucial to understanding blood components and related disorders, the lavender or pink-topped evacuated tube is the standard choice. Its distinctive color signifies the presence of Potassium EDTA (ethylenediaminetetraacetic acid) as an anticoagulant.

Why Potassium EDTA is Key for Hematology

Potassium EDTA works by chelating (binding to) calcium ions, which are essential for blood clotting. By removing these calcium ions, EDTA effectively prevents blood from coagulating, allowing for accurate analysis of cellular components. This is crucial for hematology, as it preserves the morphology and integrity of red blood cells, white blood cells, and platelets.

Common hematology tests performed using blood collected in lavender or pink-topped tubes include:

  • Complete Blood Count (CBC): This comprehensive test measures the number of red blood cells, white blood cells, and platelets, providing vital information on their size and characteristics.
  • Differential White Blood Cell Count: Identifies and quantifies the different types of white blood cells, crucial for diagnosing infections or other immune disorders.
  • Erythrocyte Sedimentation Rate (ESR): Measures the rate at which red blood cells settle, serving as an indicator of inflammation or disease activity.
  • Hemoglobin A1c (HbA1c): While often associated with diabetes management, this test, measuring average blood glucose levels over several months, utilizes EDTA blood.
  • Reticulocyte Count: Measures the number of immature red blood cells, indicating bone marrow activity and its response to anemia.
  • Blood Bank Testing: Pink-topped tubes, specifically designed for blood typing and crossmatching in blood transfusions, also contain EDTA.

Common Blood Collection Tubes Overview

The color of an evacuated tube cap provides a quick visual cue about the additive inside and the types of laboratory tests for which the tube is intended. Understanding these distinctions is fundamental for proper sample collection.

Tube Cap Color Additive Common Laboratory Tests
Lavender or Pink Potassium EDTA Hematology and Blood Bank
Gray Sodium fluoride, and sodium or potassium oxalate Glucose (especially when testing will be delayed), blood alcohol, lactic acid
Red No additive / Clot activator (plastic) Serum chemistry, serology, blood banking (some uses)
Light Blue Sodium Citrate Coagulation studies (e.g., Prothrombin Time - PT, Activated Partial Thromboplastin Time - PTT)
Green Heparin (lithium, sodium, or ammonium) Plasma chemistry, STAT electrolytes, ammonia

Note: The table above highlights common tube types and their uses based on standard laboratory practices, including specific details from available information for lavender/pink and gray tubes.

Importance of Proper Tube Selection

Selecting the correct blood collection tube is paramount for accurate diagnostic testing. Using the wrong tube can lead to inaccurate results, necessitate re-collection, and delay patient care. The specific additive in each tube is designed to ensure sample integrity for particular analytical methods. For hematology, the EDTA in lavender/pink tubes ensures that blood cells remain in their natural state, preventing clotting that would interfere with cell counts and morphological examinations, thereby enabling precise diagnostic outcomes.