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Can BC affect thyroid?

Published in Hormone Interactions 2 mins read

Yes, birth control (BC), specifically oral contraceptives containing estrogen or a combination of estrogen and progesterone, can affect thyroid function.

How Birth Control Interacts with Thyroid Hormones

The primary mechanism by which birth control pills can influence the thyroid involves the hormone estrogen. Estrogen, present in many oral contraceptives, increases the amount of thyroid binding proteins (TBPs) in your body.

Thyroid hormones exist in two forms:

  • Free thyroid hormones: These are unbound and biologically active, meaning they are available for your body's cells to use.
  • Bound thyroid hormones: These are attached to proteins, like TBPs, and are not immediately available for use.

When birth control pills increase the number of TBPs, more thyroid hormone gets bound. This can alter the delicate balance between free and bound thyroid hormones, potentially leading to a decrease in the amount of free, active thyroid hormone available to your tissues.

Key Effects on Thyroid Hormone Balance

The interaction can be summarized as follows:

Component in BC Effect on Thyroid Hormones Impact on Free Thyroid Hormone
Estrogen Increases Thyroid Binding Proteins (TBPs) Decreases availability (as more gets bound)
TBPs Bind to thyroid hormones Reduces immediate biological activity

Implications for Thyroid Health

For individuals with a healthy thyroid, the body often compensates for the increased binding proteins by producing more thyroid hormone. However, for those with pre-existing thyroid conditions, especially hypothyroidism, or those taking thyroid hormone replacement medication, this effect can be significant.

Considerations:

  • For individuals with Hypothyroidism: If you are taking thyroid hormone medication (like levothyroxine), the increased binding proteins caused by birth control could mean that less of your prescribed hormone is available to your body's cells. This might necessitate an adjustment in your medication dosage.
  • Monitoring Thyroid Function: If you start or stop birth control pills, especially if you have a thyroid condition, it's advisable to have your thyroid function monitored by a healthcare provider. They can assess your thyroid-stimulating hormone (TSH) levels and free thyroid hormone levels to determine if any adjustments are needed.
  • Discussion with Your Doctor: Always discuss your birth control options and any existing medical conditions, including thyroid disorders, with your doctor. They can help you choose the most appropriate birth control method and manage any potential interactions.