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How do you know if your SHBG is low?

Published in Hormone Levels 2 mins read

The most definitive way to know if your Sex Hormone Binding Globulin (SHBG) is low is through a blood test. However, certain physical signs and symptoms, particularly in women, can also suggest lower levels.

What is SHBG?

Sex Hormone Binding Globulin (SHBG) is a protein produced by the liver that binds to sex hormones, such as testosterone and estrogen. By binding to these hormones, SHBG controls how much of them are "free" and active in your body. When SHBG levels are low, more free hormones are available, which can lead to various effects.

Diagnosing Low SHBG

1. Blood Test

The primary and most accurate method to determine your SHBG level is a simple blood test. A healthcare provider can order this test, often as part of a broader hormone panel, to measure the amount of SHBG circulating in your bloodstream. The results will indicate whether your levels fall within the normal, low, or high range.

2. Clinical Signs and Symptoms

While a blood test provides a definitive diagnosis, certain physical signs and symptoms can indicate that your SHBG levels might be low, especially in women. These symptoms often arise due to an increase in free testosterone circulating in the body.

Common Signs of Low SHBG in Women:

Low SHBG is frequently associated with conditions like Polycystic Ovarian Syndrome (PCOS). If you experience several of these signs, it may be beneficial to discuss them with a healthcare professional:

Symptom Category Specific Manifestations
Hair Changes Male-patterned hair growth (hirsutism) on the face, chest, or back, or male-patterned hair loss (androgenic alopecia).
Menstrual Cycle Irregular periods, infrequent periods, or absence of menstruation.
Physical Changes Decreased breast tissue.
Skin Issues Acne, oily skin, or other skin abnormalities.

These symptoms are often linked to a hormonal imbalance where there's an excess of free androgens (male hormones) due to insufficient SHBG to bind them.

When to Consult a Doctor

If you suspect your SHBG levels might be low based on the symptoms you are experiencing, or if you have a condition like PCOS, it is important to consult a healthcare provider. They can perform the necessary blood tests, interpret the results in the context of your overall health, and recommend appropriate management strategies if needed. Self-diagnosis based solely on symptoms is not sufficient.