The frequency of Human Chorionic Gonadotropin (hCG) administration while on Testosterone Replacement Therapy (TRT) is determined by your specific fertility goals, particularly if you are trying to maintain or restore sperm production.
hCG Administration Protocols with TRT
Different strategies for incorporating hCG exist, depending on whether you are actively pursuing pregnancy in the short term or planning for it further in the future.
For Maintaining Fertility While Continuing TRT (Pregnancy Desired Within 6-12 Months)
If you are undergoing TRT and desire to achieve pregnancy within a 6 to 12-month timeframe, it is possible to continue your TRT while simultaneously administering hCG to support testicular function and sperm production.
- Dosage & Frequency: You may be prescribed 500 IU of hCG every other day. In some cases, clomiphene citrate may also be used alongside this regimen.
For Fertility Planning (Pregnancy Desired Beyond 12 Months) – Cyclical Approach
For men on TRT who are planning for pregnancy in a period greater than 12 months, a different strategy might be employed. This approach involves temporarily cycling off TRT to allow for a focused period of hCG use to stimulate sperm production.
- Protocol: This typically involves pausing TRT every six months for a dedicated four-week cycle. During this four-week period, you would take 3,000 IU of hCG every other day. After the four-week cycle, TRT can be resumed.
Summary of hCG Protocols for Men on TRT
The following table summarizes the key protocols for hCG use in men undergoing TRT, based on fertility intentions:
| Fertility Goal | TRT Status During hCG Use | hCG Dosage & Frequency | Notes |
|---|---|---|---|
| Pregnancy within 6-12 months | TRT continued | 500 IU every other day | Can be co-administered with clomiphene citrate |
| Pregnancy beyond 12 months | TRT paused (for a 4-week cycle) | 3,000 IU every other day (during the 4-week cycle) | This 4-week cycle occurs every six months while TRT is paused |
For more detailed information on male fertility and hormone therapy, you can refer to reputable health resources, such as those provided by leading medical institutions.
