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Where is the smc3 gene located?

Published in Human Gene Location 1 min read

The SMC3 gene is precisely located on Chromosome 10 in humans, at the 10q25.2 band.

Understanding SMC3 Gene Location

The SMC3 (Structural Maintenance of Chromosomes 3) gene is essential for proper cell function, playing vital roles in chromosome structure, DNA repair, and gene regulation. Pinpointing its exact position on the human genome is crucial for understanding its function and implications in health and disease.

Detailed Location Information

For humans, the specific location of the SMC3 gene is outlined below:

Characteristic Detail
Chromosome Chromosome 10
Band 10q25.2

Decoding the Location Terminology

  • Chromosome 10: In humans, genes are organized into 23 pairs of chromosomes. Chromosome 10 is an autosome, meaning it is not a sex chromosome.
  • 10q25.2: This alphanumeric code provides a detailed address for the gene on the chromosome:
    • 10 refers to Chromosome 10.
    • q designates the "long arm" of the chromosome. Chromosomes have two arms, a shorter 'p' arm and a longer 'q' arm.
    • 25.2 indicates the specific region (2), band (5), and sub-band (.2) on the long arm. This hierarchical numbering system allows for precise identification of gene locations, which is critical for genetic research and clinical diagnostics.

Knowing the exact chromosomal location of genes like SMC3 is fundamental for geneticists and researchers studying human biology and genetic conditions.