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What is the Best Nasal Spray for Treating Severe Hypoglycemia in Diabetics?

Published in Hypoglycemia Treatment 3 mins read

The best and currently only dry nasal spray specifically designed to treat severe low blood sugar (severe hypoglycemia) in people with diabetes is BAQSIMI®. This innovative product provides a crucial, needle-free option for emergency glucagon administration.

Understanding BAQSIMI®: The Glucagon Nasal Powder

BAQSIMI® is a dry nasal spray that delivers glucagon, a hormone that helps raise blood sugar levels quickly during an emergency. It is approved for use in individuals with diabetes ages 4 years and above. Its primary role is to treat severe hypoglycemia, a dangerous condition where blood glucose levels drop to critically low points, often requiring immediate intervention.


Key Features of BAQSIMI®:

  • Needle-Free Administration: Unlike traditional glucagon injections, BAQSIMI® is administered as a powder into one nostril, making it easier and less intimidating for caregivers or family members to use during an emergency.
  • Rapid Action: Glucagon works quickly to release stored glucose from the liver, helping to elevate blood sugar levels in minutes.
  • Convenient Form: Its compact and dry powder form makes it easy to carry and store, ensuring it's readily available when needed.

Why is a Nasal Spray for Hypoglycemia Important?

Severe hypoglycemia is a medical emergency that can lead to confusion, seizures, unconsciousness, and in severe cases, be life-threatening if not treated promptly. Traditional glucagon rescue kits require preparation and injection, which can be challenging under stressful emergency conditions.

The development of a nasal spray like BAQSIMI® simplifies the treatment process significantly. It allows for quick action without the need for needles or reconstitution, offering a user-friendly solution for individuals experiencing severe low blood sugar, especially when they are unable to self-treat.

Important Considerations and Warnings

While BAQSIMI® is a vital tool for managing severe hypoglycemia, it's crucial to be aware of certain considerations:

  • Contraindication: BAQSIMI® should not be used if you have a tumor in the gland on top of your kidneys (adrenal gland) called pheochromocytoma.
  • Emergency Use: This nasal spray is for emergency use only to treat severe low blood sugar. Always seek immediate medical attention after administering BAQSIMI®, even if the person appears to recover.
  • Not for Routine Lows: It is not intended for managing mild or moderate low blood sugar episodes, which can usually be treated with fast-acting carbohydrates.
  • Storage and Expiration: Ensure you store BAQSIMI® as directed and check its expiration date regularly.

Comparison to Other Glucagon Options

While BAQSIMI® is the only dry nasal spray for severe hypoglycemia, it serves as an alternative to injectable glucagon. The choice between a nasal spray and an injection often comes down to ease of use and individual preference in an emergency scenario.


Feature BAQSIMI® (Glucagon Nasal Powder) Traditional Injectable Glucagon
Administration Dry nasal spray, no needles involved Injection (subcutaneous or intramuscular)
Ease of Use Generally considered easier and quicker for caregivers Requires mixing and injection skill
Form Single-dose device, ready to use Vial and syringe, requires reconstitution
Age Appropriateness Ages 4 years and above Varies by product, generally similar
Purpose Emergency treatment of severe hypoglycemia Emergency treatment of severe hypoglycemia
Key Benefit Needle-free, less anxiety for users and caregivers Long-standing, effective method


Always consult with your healthcare provider to discuss the most appropriate glucagon rescue option for your diabetes management plan.