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What not to eat during immunotherapy?

Published in Immunotherapy Diet Restrictions 5 mins read

During immunotherapy, adjusting your diet is a critical step to support your treatment, manage potential side effects, and minimize health risks. It's generally advised to be highly selective about what you consume.

Understanding Dietary Restrictions During Immunotherapy

Proper nutrition plays a significant role in helping your body tolerate cancer treatment. Certain foods can interfere with the effectiveness of your therapy, increase your risk of infection, or exacerbate side effects. Therefore, it's essential to understand which foods to limit or avoid entirely.

Foods to Strictly Avoid

These foods carry specific risks that can be particularly detrimental when your immune system is compromised or when interacting with medication.

  • Raw or Undercooked Foods

    • Why: These foods pose a high risk of bacterial, viral, or parasitic infections, which can be dangerous when your immune system is weakened by treatment.
    • Examples:
      • Rare or medium-rare meat, poultry, and fish
      • Sushi, sashimi, or ceviche
      • Runny egg yolks or foods containing raw eggs (e.g., homemade mayonnaise, certain salad dressings)
      • Uncooked sprouts (alfalfa, clover, radish)
      • Soft, unpasteurized cheeses (e.g., feta, brie, blue cheese, queso fresco)
      • Unpasteurized dairy products (milk, yogurt)
      • Unpasteurized fruit juices or ciders
      • Cold deli meats (unless thoroughly reheated to steaming)
    • Practical Insight: Always ensure meats are cooked to their recommended internal temperatures. For guidance on safe cooking temperatures, consult resources like the U.S. Department of Agriculture.
  • Grapefruit and Grapefruit Juice

    • Why: Grapefruit can interact with various medications, including some cancer treatments, by affecting how your body metabolizes them. This can lead to increased drug levels in your system, potentially causing more severe side effects or toxicity.
    • Recommendation: Always check with your oncology team about specific food-drug interactions, as other citrus fruits might also need to be limited depending on your specific medication.
  • Alcohol

    • Why: Alcohol can exacerbate common immunotherapy side effects like fatigue, nausea, and dehydration. It can also interfere with the liver's ability to process medications and may weaken the immune system further.
    • Recommendation: It's generally advised to abstain from alcohol during immunotherapy.
  • Certain Herbal Supplements

    • Why: Many herbal supplements can interact unpredictably with immunotherapy drugs, potentially reducing their effectiveness or increasing their toxicity.
    • Practical Insight: Always inform your healthcare provider about all supplements, vitamins, and over-the-counter medications you are taking or considering. Do not start any new supplements without prior consultation.

Foods to Limit or Mostly Avoid

While not strictly forbidden for everyone, reducing your intake of these foods can support your overall health and well-being during immunotherapy.

  • Red Meat

    • Why: Red meat, especially fatty cuts, can be high in saturated fats and has been associated with inflammation. It's generally recommended to mostly avoid or significantly reduce your consumption during treatment.
    • Examples: Beef, lamb, pork, processed meats (sausages, bacon).
  • Simple Carbohydrates and Hyperglycemic Foods and Drinks

    • Why: These foods cause rapid spikes in blood sugar, which can contribute to inflammation and may negatively impact energy levels and overall metabolic health during treatment. It's best to mostly avoid them.
    • Examples:
      • Sugary drinks (soda, sweetened teas, fruit juices with added sugar)
      • White bread, white pasta, white rice
      • Pastries, cakes, cookies, candy
      • Highly processed snacks (chips, crackers)
    • Practical Insight: Opt for complex carbohydrates like whole grains, brown rice, and plenty of fruits and vegetables instead, as they provide sustained energy and essential nutrients.
  • Highly Processed Foods

    • Why: Processed foods often contain unhealthy fats, excessive sugar, sodium, and artificial additives. They typically lack essential nutrients and can contribute to inflammation and a less-than-optimal gut environment, which is crucial during treatment.
    • Examples: Fast food, packaged meals, many frozen dinners, sugary cereals.

The Importance of Food Safety

Beyond avoiding specific foods, practicing stringent food safety is paramount to prevent foodborne illnesses, which can be severe for individuals undergoing immunotherapy.

  • Wash Your Hands: Always wash hands thoroughly with soap and water before and after handling food.
  • Wash Produce: Rinse all fresh fruits and vegetables under running water, even if they have a peel.
  • Cook Thoroughly: Cook all meats, poultry, and seafood to their safe internal temperatures.
  • Avoid Cross-Contamination: Use separate cutting boards and utensils for raw meats and fresh produce.
  • Check Expiration Dates: Discard any food that is past its expiration date or shows signs of spoilage.
  • Refrigerate Promptly: Store perishable foods in the refrigerator within two hours of cooking or purchasing.

What to Prioritize Instead

While focusing on what to avoid, remember to incorporate foods that are beneficial. A diet rich in nutrient-dense foods can support your body during treatment. Consider significantly adding fruits and vegetables to your diet. For protein and healthy oils, turn to fish and nuts, which are excellent sources that can provide beneficial nutrients. For more information on supportive nutrition during cancer treatment, you can refer to resources from organizations like the American Cancer Society and the Mayo Clinic.

Category Foods to Avoid/Limit Potential Risks During Immunotherapy
Infection Risk Raw or undercooked meats, poultry, seafood, eggs; unpasteurized dairy/juices; unwashed produce; deli meats (unless reheated); uncooked sprouts Bacterial, viral, or parasitic infections due to a compromised immune system
Drug Interaction Grapefruit, grapefruit juice; certain herbal supplements Can interfere with drug metabolism, reducing efficacy or increasing toxicity
Inflammation/Health Red meat (mostly avoid); simple carbohydrates; hyperglycemic foods and drinks; highly processed foods May promote inflammation, negatively impact energy levels, contribute to side effects, or hinder recovery
Overall Wellness Alcohol Can exacerbate side effects (fatigue, dehydration), interact with medications, burden organs

Always consult with your oncology team or a registered dietitian specializing in cancer care for personalized dietary advice tailored to your specific treatment plan and health needs.