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How big do follicles need to be for a trigger shot?

Published in IVF Follicle Size 3 mins read

For an IVF trigger shot, the ideal follicle size is typically around 17 to 18 millimeters in diameter, particularly when two to three follicles have reached this measurement. This size range is crucial as it indicates the optimal maturity for egg retrieval.

Understanding Follicle Size and the Trigger Shot

The trigger shot, usually administered as part of an In Vitro Fertilization (IVF) cycle, is a critical step designed to induce the final maturation of eggs within the ovarian follicles. Its precise timing is vital for the success of the subsequent egg retrieval procedure.

Key Size Indicators:

  • Trigger Shot Target: Fertility specialists aim for follicles to be approximately 17 to 18 millimeters (mm) in diameter. This range suggests that the eggs inside are mature enough for retrieval.
  • Egg Retrieval Window: While 17-18mm is ideal for the trigger, the general ideal follicle size for egg retrieval itself typically ranges from 15 to 22 millimeters. The trigger shot timing aligns with this broader window to ensure the best possible outcome.

Why Follicle Size Matters

The size of the follicles directly correlates with the maturity and viability of the eggs they contain.

  • Underdeveloped Follicles: Follicles that are too small (e.g., less than 15mm) likely contain immature eggs that may not fertilize or develop properly.
  • Overly Mature Follicles: Follicles that are significantly larger than the ideal range might contain over-mature or post-mature eggs, which can also affect their quality and ability to fertilize.

Monitoring Follicle Development

Throughout an IVF cycle, follicle growth is meticulously monitored through regular ultrasounds and blood tests.

  • Ultrasound Scans: These scans allow fertility specialists to measure the size of individual follicles and track their growth progression.
  • Hormone Levels: Blood tests, particularly for estradiol (estrogen), provide insights into the activity of the growing follicles, helping to determine the best time for the trigger shot.

Ideal Follicle Size Overview

Stage Ideal Follicle Diameter (mm) Key Consideration
Trigger Shot 17 – 18 mm When 2-3 leading follicles reach this size
Egg Retrieval 15 – 22 mm Broader range, includes optimal sizes post-trigger

Once the leading follicles reach the optimal 17-18mm size, and other clinical indicators align, the trigger shot is administered. Egg retrieval is then typically scheduled about 34 to 36 hours later, precisely timed to coincide with the eggs' final maturation and release from the follicle walls. This precise timing is crucial for maximizing the number of mature, retrievable eggs.

For more detailed information on fertility treatments, consider consulting a reputable fertility clinic Fertility Insights.