Leqembi is contraindicated for individuals who have experienced a serious hypersensitivity reaction to lecanemab-irmb or to any of the inactive ingredients (excipients) found in Leqembi.
Understanding Leqembi Contraindications
This specific contraindication means that if a patient has a history of a severe allergic reaction or an extreme immune response to the active drug component (lecanemab-irmb) or any other substance used in the formulation of Leqembi, they should not be administered this medication. Such reactions could include severe systemic responses like anaphylaxis or angioedema.
Here are the specific patient groups who cannot take Leqembi:
- Patients with Serious Hypersensitivity to Lecanemab-irmb: This includes individuals who have had a severe allergic or immune reaction specifically to lecanemab-irmb, which is the active therapeutic ingredient in Leqembi.
- Patients with Serious Hypersensitivity to Leqembi Excipients: If a patient has a documented history of severe allergic reactions to any of the non-active components (excipients) used in Leqembi's formulation, they are also contraindicated.
Key Groups Who Cannot Receive Leqembi
To provide a clear overview, the table below summarizes the specific conditions under which Leqembi is contraindicated:
| Condition | Who Cannot Take Leqembi? | Explanation |
|---|---|---|
| Serious Hypersensitivity to Lecanemab-irmb | Yes | Individuals with a history of a severe allergic or immune reaction to the active drug component of Leqembi. |
| Serious Hypersensitivity to Leqembi Excipients | Yes | Patients who have experienced severe allergic reactions to any of the inactive ingredients in Leqembi. |
In essence, any patient with a known history of a serious allergic or immune reaction to either the active medication or its inactive components is not a candidate for Leqembi treatment.
