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How Long Does It Take for Meatloaf to Cook at 350 Degrees?

Published in Meatloaf Cooking Time 2 mins read

The cooking time for meatloaf at 350 degrees Fahrenheit (350°F) primarily depends on its weight and thickness. To ensure it is fully cooked and safe to eat, meatloaf should reach an internal temperature of 160°F.

Meatloaf Cooking Times at 350°F

Here's a general guide for how long different sizes of meatloaf typically take to cook when baked at 350°F:

Meatloaf Weight Approximate Cooking Time at 350°F
1 pound 35 to 45 minutes
2 pounds 1 hour to 1 hour 20 minutes
3 pounds 1 hour 30 minutes to 2 hours

It's crucial to use a reliable meat thermometer to verify the internal temperature, as cooking times can vary based on the meatloaf's shape (loaf pan vs. free-form), ingredients, and oven calibration.

Tips for Perfect Meatloaf Doneness

Achieving the perfect meatloaf involves more than just setting a timer. Here are some essential tips:

  • Use a Meat Thermometer: This is the most accurate way to determine doneness. Insert the thermometer into the center of the meatloaf, ensuring it doesn't touch the bottom of the pan. The meatloaf is safely cooked when it reaches an internal temperature of 160°F.
  • Consider Meatloaf Shape: A meatloaf baked in a loaf pan may cook slightly differently than one shaped free-form on a baking sheet, as the pan retains heat and can influence even cooking.
  • Resting Time: Once cooked, allow the meatloaf to rest for 5-10 minutes before slicing. This allows the juices to redistribute throughout the loaf, resulting in a more moist and flavorful meal.

Following these guidelines will help ensure your meatloaf is delicious, juicy, and cooked to a safe temperature every time.