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Who Should Not Take NAD?

Published in NAD+ Supplement Contraindications 2 mins read

Individuals with specific health conditions or life stages should exercise caution or avoid taking NAD+ supplements.

Key Considerations for NAD+ Supplementation

While NAD+ (Nicotinamide Adenine Dinucleotide) supplements are gaining attention for their potential health benefits, it's crucial to understand that they are not suitable for everyone. Certain populations should be particularly cautious or abstain from their use due to potential risks or insufficient research.

Groups Advised to Exercise Caution or Avoid NAD+

  • Individuals with Liver Issues: People who have pre-existing liver conditions.
  • Individuals with Kidney Issues: Those with compromised kidney function.
  • Pregnant Individuals: Women who are currently pregnant.
  • Breastfeeding Individuals: Mothers who are breastfeeding.

Detailed Reasons for Caution

Liver and Kidney Conditions

The liver and kidneys play a vital role in processing and metabolizing substances introduced into the body, including NAD+ supplements. When these organs are already compromised, taking additional supplements can place an undue burden on them. The intricate pathways involved in the metabolism of NAD+ supplements specifically rely on healthy liver and kidney function for efficient processing and elimination. Therefore, to prevent potential complications or further strain on these crucial organs, individuals with pre-existing liver or kidney issues are generally advised to avoid NAD+ supplementation.

Pregnancy and Breastfeeding

For pregnant and breastfeeding individuals, the primary reason for caution regarding NAD+ supplements is the lack of comprehensive research. There is currently insufficient scientific data to definitively determine the safety and potential long-term effects of NAD+ supplementation on fetal development, infant health, or the health of the mother during these critical periods. Given the potential for unforeseen impacts on such vulnerable populations, it is recommended that pregnant and breastfeeding individuals err on the side of caution and abstain from taking NAD+ supplements until more extensive research confirms their safety.

Summary of NAD+ Avoidance Recommendations

To provide a clear overview, the table below summarizes the groups who should not take NAD+ and the underlying reasons:

Group Reason for Caution/Avoidance
Individuals with Liver Issues Organs are key for metabolism of NAD+ supplements; may cause strain.
Individuals with Kidney Issues Organs are key for metabolism of NAD+ supplements; may cause strain.
Pregnant Individuals More research is needed to determine potential harms.
Breastfeeding Individuals More research is needed to determine potential harms.

It is always advisable to consult with a healthcare professional before starting any new supplement regimen, especially if you fall into any of the above categories.