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How to Treat High Neutrophils?

Published in Neutrophilia Treatment 4 mins read

Treating high neutrophils, a condition known as neutrophilia, primarily involves identifying and addressing the underlying cause of the elevated count. Neutrophilia typically occurs when the body is fighting an infection or inflammation resulting from an illness or injury, meaning the high count is often a symptom, not the root problem itself.

Identifying the Underlying Cause

Since high neutrophil levels are a response to a deeper issue, the first step in treatment is an accurate diagnosis by a healthcare professional. They will consider your medical history, symptoms, and may perform various tests, including a complete blood count (CBC) with differential, to pinpoint why your body is producing more neutrophils.

Common reasons for elevated neutrophils include:

  • Infections: Especially bacterial infections, but also some viral or fungal infections.
  • Inflammation: This can stem from various sources, such as:
    • Injuries: Physical trauma, burns, or surgery.
    • Autoimmune diseases: Conditions like rheumatoid arthritis or inflammatory bowel disease.
    • Stress: Severe emotional or physical stress.
    • Tissue damage: From conditions like a heart attack.
  • Certain Medications: Corticosteroids are a common culprit.
  • Cancers: Some types of cancer can cause neutrophilia, particularly those affecting the bone marrow or chronic myeloid leukemia.
  • Smoking: Chronic smoking can lead to persistently elevated neutrophil counts.

Treatment Approaches Based on Cause

Lowering neutrophil levels directly depends on effectively treating the root cause. Here's a breakdown of common treatment strategies:

Bacterial Infections

When neutrophilia is due to a bacterial infection, antibiotic therapy is often prescribed. The specific antibiotic will depend on the type of bacteria identified and its susceptibility to different drugs. Completing the full course of antibiotics, even if symptoms improve, is crucial to fully eradicate the infection and prevent recurrence.

Inflammatory Conditions

For inflammation, treatment focuses on managing or resolving the inflammatory process. This might involve:

  • Anti-inflammatory Medications: Non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids may be used to reduce acute inflammation.
  • Targeted Therapies: For autoimmune diseases, specific medications that modulate the immune system are prescribed to control the underlying condition.
  • Rest and Recovery: For injuries, allowing the body to heal is essential.

Other Causes

  • Medication Adjustment: If a medication is causing high neutrophils, your doctor may adjust the dosage or switch you to an alternative.
  • Stress Management: For stress-induced neutrophilia, techniques like mindfulness, exercise, and therapy can help manage stress levels.
  • Smoking Cessation: Quitting smoking is vital for reducing inflammation and improving overall health.
  • Cancer Treatment: If cancer is the cause, treatment will involve chemotherapy, radiation, surgery, or targeted therapies as determined by an oncologist.

Summary of Causes and Treatments

Underlying Cause Common Symptoms Potential Treatment Approaches
Bacterial Infections Fever, localized pain, pus, general malaise Antibiotic therapy (e.g., penicillin, amoxicillin, doxycycline), sometimes surgical drainage for abscesses.
Inflammatory Conditions Pain, swelling, redness, stiffness, fatigue Anti-inflammatory drugs (NSAIDs, corticosteroids), disease-modifying antirheumatic drugs (DMARDs) for autoimmune conditions, rest, physical therapy.
Physical Injury/Trauma Localized pain, swelling, bruising Rest, immobilization, pain management, physical therapy, surgery if needed.
Severe Stress Anxiety, insomnia, fatigue, muscle tension Stress reduction techniques (meditation, yoga, exercise), cognitive-behavioral therapy (CBT), adequate sleep.
Certain Medications Elevated neutrophil count, other drug side effects Medication adjustment or cessation under medical supervision, switching to alternative drugs.
Smoking Chronic cough, shortness of breath, lung issues Smoking cessation programs, nicotine replacement therapy, medications to aid quitting.
Bone Marrow Disorders/Cancers Fatigue, weight loss, night sweats, recurrent infections Chemotherapy, radiation therapy, targeted therapies, stem cell transplant, immunotherapy, supportive care tailored to the specific diagnosis. Learn more about bone marrow disorders

It is crucial to consult a healthcare provider if you have elevated neutrophil levels, as self-treating the symptom without addressing the underlying cause can be ineffective and potentially harmful. A medical professional can accurately diagnose the reason for your neutrophilia and recommend the most appropriate course of action.