Sheffield Wednesday's worst loss was a 0–10 defeat against Aston Villa. This substantial loss occurred in the Football League.
This record-setting match stands as the club's heaviest Football League defeat and represents the largest margin of loss they have ever endured. While Sheffield Wednesday has experienced other significant defeats in various competitions, the 0–10 scoreline against Aston Villa is the most severe in their history.
Here is a summary of some of Sheffield Wednesday's notable record defeats:
| Category | Opponent | Score |
|---|---|---|
| Heaviest Football League Defeat | Aston Villa | 0–10 |
| Heaviest Cup Defeat | Blackburn Rovers | 1–6 |
