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Does SKYRIZI Affect Joints?

Published in SKYRIZI Side Effects 3 mins read

Yes, SKYRIZI can affect joints in multiple ways: it is specifically designed to treat inflammatory conditions that impact joints, and for some individuals, joint pain can also be a reported side effect.

SKYRIZI's Role in Joint Conditions

SKYRIZI (risankizumab) is a targeted medication used to manage various chronic inflammatory diseases. It works by blocking specific proteins in the body that contribute to inflammation. In conditions like psoriatic arthritis, which directly affects the joints, SKYRIZI plays a crucial role in reducing inflammation. This action helps to alleviate symptoms such as joint pain, stiffness, and swelling, ultimately aiming to improve joint function and prevent further damage to the joints.

Joint Pain as a Potential Side Effect

While SKYRIZI is effective in managing joint-related inflammation for certain conditions, it's important to be aware that joint pain has been identified as a potential side effect for some patients. Specifically, among individuals undergoing treatment for Crohn's disease and ulcerative colitis, joint pain is listed among the common side effects.

Other common side effects observed in people treated for Crohn's disease and ulcerative colitis include:

  • Upper respiratory infections
  • Headache
  • Stomach (abdominal) pain
  • Injection site reactions
  • Low red blood cells (anemia)
  • Fever
  • Back pain
  • Urinary tract infection
  • Rash

Common Side Effects of SKYRIZI (for Crohn's and Ulcerative Colitis)

Side Effect Description
Joint Pain A sensation of aching, discomfort, or soreness in the joints.
Upper Respiratory Infections Infections affecting the nose, throat, or sinuses (e.g., common cold).
Headache Pain or discomfort experienced in the head.
Stomach (Abdominal) Pain Discomfort or pain in the stomach or belly area.
Injection Site Reactions Localized reactions such as redness, swelling, or pain where the injection was given.
Low Red Blood Cells (Anemia) A condition characterized by a reduced number of red blood cells, potentially causing fatigue.
Fever An elevated body temperature.
Back Pain Discomfort or pain in the back region.
Urinary Tract Infection An infection affecting any part of the urinary system.
Rash An area of inflamed, discolored, or textured skin.

What to Do If You Experience Joint Pain

If you are taking SKYRIZI and experience new or worsening joint pain, it is essential to communicate with your healthcare provider. They can assess your symptoms, determine if the joint pain is related to the medication or another factor, and provide appropriate guidance. Always discuss any concerns or side effects with your doctor and never adjust your medication dosage or stop treatment without their professional advice.