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What Should My Significance Level Be?

Published in Statistical Hypothesis Testing 5 mins read

For most research and analytical purposes, the most commonly accepted significance level, often denoted as alpha (α), is 0.05. This value represents the probability of incorrectly rejecting a true null hypothesis, also known as a Type I error.

Understanding the Significance Level (α)

The significance level is a critical threshold in hypothesis testing. When you conduct a statistical test, you're usually trying to determine if there's enough evidence to reject a null hypothesis, which typically states there's no effect or no difference. Your chosen alpha level dictates how much risk you're willing to take of making a "false positive" conclusion.

  • Type I Error (False Positive): Rejecting the null hypothesis when it is, in fact, true. Your alpha (α) is the probability of committing this error.
  • Type II Error (False Negative): Failing to reject the null hypothesis when it is, in fact, false. The probability of this error is denoted as beta (β).

If your p-value (the probability of observing your data, or more extreme data, if the null hypothesis were true) is less than or equal to your chosen alpha level, you typically reject the null hypothesis.

Why 0.05 is the Common Standard

The 0.05 alpha level has become a widely adopted convention across many scientific and social science disciplines. It strikes a balance, being neither too stringent (which could lead to missing real effects) nor too lenient (which could lead to claiming effects that don't exist). This level means you are willing to accept a 5% chance of being wrong when you conclude there is a significant effect or relationship.

Factors Influencing Your Choice of Alpha

While 0.05 is standard, the appropriate alpha level can vary depending on your specific field of study, the nature of your research question, and the potential consequences of making a Type I or Type II error.

1. Field or Discipline Standards

Different academic and professional fields can have their own established conventions for appropriate alpha levels. For instance:

  • Medical Research: In studies involving new drug approvals or life-saving interventions, a much lower alpha level like 0.01 or even 0.001 might be chosen. This reduces the risk of approving an ineffective or harmful treatment.
  • Physics/High-Energy Particle Research: Some discoveries, such as the Higgs boson, required extremely stringent alpha levels (e.g., 0.0000003 or "5 sigma") to declare a finding, due to the immense resources and fundamental implications involved.
  • Exploratory Research/Pilot Studies: In preliminary studies where the goal is to identify potential areas for further investigation rather than definitive proof, a higher alpha level like 0.10 might be acceptable to avoid missing potentially interesting trends.

2. Consequences of Errors

Consider the real-world implications of each type of error:

  • Reducing Type I Error Risk (Lower Alpha, e.g., 0.01): If a false positive finding would be costly, dangerous, or lead to significant misallocation of resources, you should choose a lower alpha. Examples include:
    • Quality control in manufacturing (e.g., declaring a product safe when it's not).
    • Legal decisions (e.g., wrongly convicting an innocent person).
  • Reducing Type II Error Risk (Higher Alpha, e.g., 0.10): If a false negative finding (missing a real effect) would be more detrimental, you might accept a higher alpha to increase your power to detect an effect. Examples include:
    • Screening for a rare but treatable disease (better to have some false positives than miss a true case).
    • Early-stage drug discovery (don't want to discard a promising compound too early).

3. Sample Size and Statistical Power

Your choice of alpha also impacts your statistical power, which is the probability of correctly rejecting a false null hypothesis (1 - β).

  • Lowering alpha (e.g., from 0.05 to 0.01) makes it harder to reject the null hypothesis, thus decreasing power. This means you're less likely to detect a real effect if one exists.
  • Increasing alpha (e.g., from 0.05 to 0.10) makes it easier to reject the null hypothesis, thus increasing power.

You might need a larger sample size to achieve sufficient power if you choose a very low alpha level.

Common Alpha Levels and Their Implications

Alpha (α) Common Use Cases Implications
0.01 High-stakes research (e.g., medical, pharmaceutical, physics), when Type I error is very costly or dangerous. Very strong evidence needed to reject the null hypothesis; lower risk of false positives.
0.05 Standard for most scientific research in social sciences, biology, business, education, etc. Balanced approach; 5% risk of false positive; widely accepted.
0.10 Exploratory research, pilot studies, preliminary investigations where missing an effect is more concerning. Weaker evidence needed to reject the null; higher risk of false positives.

Making Your Decision

When determining "your" significance level, consider these points:

  • Start with 0.05 as the default. It's the most widely accepted and understood standard.
  • Consult your field's conventions. Are there specific guidelines or common practices for the type of research you're doing?
  • Weigh the costs of errors. Which error (Type I or Type II) would be more detrimental in your specific context?
  • Justify your choice. Regardless of the alpha level you select, be prepared to explain why it is appropriate for your study design and research goals.

Ultimately, your significance level is a critical decision that balances the risk of making incorrect conclusions in your research.