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How does stroke affect breathing?

Published in Stroke Respiratory Complications 5 mins read

A stroke can significantly disrupt breathing by damaging the brain areas responsible for controlling respiration, leading to a range of breathing difficulties that can impact a patient's recovery and long-term health.

How Does Stroke Affect Breathing?

Stroke, a sudden interruption of blood flow to the brain, can severely impair the body's ability to breathe effectively in several key ways. These disruptions arise from damage to the brain's intricate breathing control centers, the pathways that send signals to respiratory muscles, and the areas governing swallowing and airway protection.

Direct Impact on the Brain's Breathing Control

The brain houses vital centers that regulate the rhythm and depth of breathing. When these areas are affected by a stroke, the coordination and efficiency of respiration can be compromised.

Disruption of Breathing Rhythm

A stroke can disturb the central rhythm generation within the brainstem, which is the primary control center for automatic breathing. Damage here can lead to:

  • Irregular Breathing Patterns: The brain's ability to maintain a steady rhythm can be lost, resulting in erratic breathing.
  • Apnea: Periods where breathing stops completely, which can be particularly dangerous during sleep (central sleep apnea).
  • Cheyne-Stokes Respiration: A pattern characterized by cycles of progressively deeper and sometimes faster breathing, followed by a gradual decrease that results in a temporary stop (apnea). This is often seen in severe strokes.

Reduced Respiratory Drive

Stroke can also interrupt the descending respiratory pathways—the neural routes that carry signals from the brain to the muscles involved in breathing, such as the diaphragm and intercostal muscles. This interruption can lead to:

  • Weakened Breathing: The muscles may not receive strong enough signals, resulting in shallow or insufficient breaths.
  • Hypoventilation: Reduced air movement in and out of the lungs, leading to inadequate oxygen intake and carbon dioxide removal.
  • Increased Work of Breathing: The body has to work harder to achieve adequate ventilation, leading to fatigue.

Impaired Airway Protection

Beyond direct control of breathing, a stroke can also affect the ability to protect the airway, leading to serious complications.

Aspiration Risk Due to Bulbar Weakness

Damage to the brainstem or specific cranial nerves can cause what is known as bulbar weakness. This affects the muscles in the mouth, throat, and larynx (voice box) responsible for swallowing and speaking.

  • Dysphagia (Difficulty Swallowing): Weakness in these muscles makes it difficult to manage saliva, food, or liquids, increasing the risk of them entering the airway.
  • Aspiration: When foreign material enters the lungs instead of the stomach, it can lead to aspiration pneumonia, a severe lung infection. This is a common and life-threatening complication for stroke survivors.
  • Weak Cough Reflex: The ability to cough effectively to clear the airway may also be impaired, further increasing aspiration risk.

Common Breathing Problems After Stroke

Many specific respiratory issues can arise after a stroke. Understanding these conditions is crucial for timely diagnosis and management.

Breathing Problem Description Potential Cause (Post-Stroke)
Cheyne-Stokes Respiration Cycles of waxing and waning breathing depth and rate, with periods of apnea. Damage to central respiratory centers (often in brainstem or severe cortical strokes).
Central Sleep Apnea Breathing repeatedly stops and starts during sleep because the brain doesn't send proper signals to the muscles that control breathing. Damage to brainstem areas controlling respiratory drive.
Obstructive Sleep Apnea Airway repeatedly collapses during sleep despite breathing effort; can be exacerbated by stroke-related muscle weakness or positioning. Weakness of pharyngeal muscles, altered sensation, obesity.
Aspiration Pneumonia Lung infection caused by inhaling food, liquid, or vomit into the lungs. Bulbar weakness leading to dysphagia and impaired cough reflex.
Hypoventilation Insufficient breathing, leading to too little oxygen and too much carbon dioxide in the blood. Reduced respiratory drive, muscle weakness, or central rhythm disturbance.
Diaphragmatic Paralysis Weakness or complete loss of function of the diaphragm, the primary breathing muscle. Damage to the phrenic nerve pathway from the brain or spinal cord.

Why Respiratory Complications Matter

Respiratory complications after a stroke can significantly worsen patient outcomes. They are a leading cause of morbidity and mortality, often resulting in:

  • Longer hospital stays and increased healthcare costs.
  • Increased risk of secondary infections and systemic complications.
  • Delayed rehabilitation and recovery.
  • Reduced quality of life.

Managing Breathing Issues Post-Stroke

Early recognition and management of breathing difficulties are critical for stroke survivors. Treatment strategies are tailored to the specific type and severity of respiratory dysfunction.

  • Airway Management: For severe cases, this may include endotracheal intubation and mechanical ventilation to support breathing.
  • Swallowing Therapy: Speech-language pathologists work with patients to improve swallowing safety, often recommending specific diets (e.g., thickened liquids, pureed foods) and swallowing exercises. Learn more about swallowing disorders after stroke.
  • Positioning: Elevating the head of the bed can reduce the risk of aspiration and improve lung expansion.
  • Pulmonary Hygiene: Techniques like deep breathing exercises, coughing assistance, and suctioning help clear secretions and prevent pneumonia.
  • Sleep Apnea Treatment: Continuous positive airway pressure (CPAP) or bi-level positive airway pressure (BiPAP) machines can be used for sleep apnea.
  • Medications: Bronchodilators or other respiratory medications may be prescribed if there is associated lung disease or bronchospasm.
  • Respiratory Muscle Training: Exercises to strengthen breathing muscles can improve respiratory function over time.
  • Monitoring: Regular assessment of oxygen levels (e.g., pulse oximetry) and breathing patterns is essential.

By addressing these potential breathing challenges comprehensively, healthcare providers can help stroke survivors achieve better recovery and reduce the risk of life-threatening complications.